Antimicrobial
OLIGOPEPTIDE-10
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic antimicrobial peptide — fights acne-causing bacteria on the skin's surface without the downsides of traditional antibiotics. Gentle and targeted.
Oligopeptide-10 is a 15-unit synthetic antimicrobial peptide composed of alanine, leucine, lysine, and phenylalanine residues. It functions by disrupting bacterial cell membranes, making it effective against Propionibacterium acnes (now Cutibacterium acnes) and other skin surface bacteria. Unlike conventional antibiotics, antimicrobial peptides are less likely to induce bacterial resistance. CosIng lists antimicrobial, deodorant, and skin conditioning functions. Being a synthetic peptide, it has good stability and specificity, though long-term cosmetic use data is still relatively limited.
Function
Skin benefits
- Targets acne-causing bacteria without antibiotics
- Low risk of bacterial resistance development
- Skin conditioning properties
- Natural deodorant function via antimicrobial activity
Known concerns
- Limited long-term safety data in cosmetics
- Efficacy depends on formulation pH and stability
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antimicrobials
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.