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Skin Conditioning

OROTIC ACID

CAS 65-86-1 Updated
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Orotic acid — a pyrimidine biosynthesis intermediate occasionally used as a skin-conditioning ingredient. PubChem flags acute oral toxicity and irritation on the raw material.

Function

SKIN CONDITIONING

Skin benefits

  • Pyrimidine precursor — biological role
  • Studied as skin-conditioning agent
  • Some antioxidant claims

Known concerns

  • GHS H302 harmful if swallowed
  • H315/H319 skin and eye irritation
  • H335 respiratory irritation
  • Niche cosmetic use, limited dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.