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Banned phenolic (Annex II)

P-CRESOL

CAS 106-44-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

P-Cresol is a corrosive phenolic compound prohibited in EU cosmetics under Annex II. It causes severe skin and eye burns and is acutely toxic, with no legitimate place in any consumer skincare or personal-care product.

Skin benefits

  • Has industrial use as a chemical intermediate and disinfectant
  • Strong antimicrobial activity in non-cosmetic settings
  • Well-studied chemistry with established analytical methods

Known concerns

  • Corrosive to skin and eyes and acutely toxic on contact or inhalation
  • Listed on EU Cosmetics Regulation Annex II as banned from cosmetics
  • Systemic toxicity affecting kidney, liver and nervous system reported
  • GHS classification includes acute toxicity and skin corrosion

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.