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Restricted hair dye intermediate

P-PHENYLENEDIAMINE SULFATE

CAS 16245-77-5
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

P-Phenylenediamine sulfate is an oxidative hair dye intermediate restricted under EU Cosmetics Regulation Annex III. It is a potent skin sensitizer linked to severe allergic contact dermatitis and is banned from eyelash and eyebrow products.

Skin benefits

  • Effective oxidative hair dye intermediate
  • Provides deep dark shades in permanent hair coloring

Known concerns

  • Strong skin sensitizer (GHS category 1)
  • Restricted in EU under Annex III with maximum on-scalp concentration limits
  • Documented cause of severe allergic contact dermatitis
  • Banned from use in eyelash and eyebrow products
  • Not permitted in non-oxidative direct dyes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related restricted hair dye intermediates

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.