[(p-Tolyloxy)methyl]oxirane

About [(p-Tolyloxy)methyl]oxirane

P-Tolyloxy)methyl]oxirane is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

This glycidyl ether compound features a p-tolyloxy substituent attached to an epoxide ring, functioning as a fragrance and flavoring material. The EU CLP classification includes H315 (skin irritation), H317 (skin sensitization), H341 (suspected mutagenicity), H319 (H320) (eye irritation), H372 (STOT repeated exposure), and H411 (aquatic chronic toxicity) with a Danger signal word. The ingredient is subject to REACH restrictions, and the SCCS has identified the glycidyl ether structure as particularly concerning for skin sensitization and potential genotoxicity. EU regulatory assessment is ongoing, with IFRA guidelines recommending strict concentration limits and the ingredient effectively restricted in cosmetic use.

Known Concerns

• ⚠ Skin sensitization (H317)
• ⚠ Skin irritation (H315)
• ⚠ Eye irritation (H319, H320)
• ⚠ Suspected mutagenicity (H341)
• ⚠ Specific target organ toxicity - repeated exposure (H372)
• ⚠ Environmental hazard - chronic aquatic toxicity (H411)
• ⚠ Danger signal word - significant hazard classification
• ⚠ Glycidyl ether structural alert for genotoxicity

References