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Skin Conditioning

PALMATINE

CAS 3486-67-7
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A plant alkaloid related to berberine, used for antimicrobial and anti-inflammatory effects. Active even at low levels; topical safety data is limited so use is best kept restrained.

Function

ANTIOXIDANT

Skin benefits

  • Berberine-family alkaloid
  • Antimicrobial and anti-inflammatory in studies
  • Used in oral and skin care
  • Potent at low concentrations

Known concerns

  • Alkaloid with documented systemic activity
  • Limited dermal safety dossier
  • Caution advised on broken skin
  • Not recommended for sensitive skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.