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Skin Conditioning

PALMITOYL D-ARGINYL TYROSINYL ORNITHINYL PHENYLALANINE AMIDE

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A palmitoyl-tagged synthetic tetrapeptide built from D-amino acids for resistance to skin enzymes — used as a conditioning signal peptide. Class is well-tolerated; sequence-specific data is sparse.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Palmitoyl-modified peptide with strong skin penetration
  • Skin conditioning and signal-peptide activity
  • D-amino-acid backbone resists enzymatic breakdown

Known concerns

  • Limited public toxicology specific to this sequence
  • Sensitisation cannot be ruled out without patch-test data
  • Quality depends on synthesis purity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.