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Skin Conditioning

PALMITOYL HISTIDYL D-PHENYLALANYL ARGININE

Updated
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A palmitic acid–anchored tripeptide of histidine, D-phenylalanine and arginine, designed for skin conditioning. The fatty acid tail improves skin compatibility; gentle at typical low use levels.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning at low use levels
  • Lipidated peptide aids skin penetration
  • Antioxidant signal from histidine residue

Known concerns

  • Limited independent clinical data
  • Possible mild sensitization in rare cases
  • Cost-driven low-dose use limits efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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ACETYL HISTIDINE
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ACETYL METHIONINE
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ACETYL SH-PENTAPEPTIDE-35
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ACETYLATED C10-40 HYDROXYALKYL ACID CHOLESTEROL/LANOSTEROL ESTERS
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ALANINE/HISTIDINE/LYSINE POLYPEPTIDE COPPER HCL
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.