Skip to content

Conditioning Agent

PALMITOYL OCTAPEPTIDE-26

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lipopeptide used in anti-aging skincare — the palmitic acid chain helps it penetrate skin to deliver peptide-based conditioning benefits. Limited but positive safety data.

Palmitoyl Octapeptide-26 is a synthetic lipopeptide formed by conjugating palmitic acid to an eight-amino-acid peptide chain. The palmitoyl group enhances skin penetration and bioavailability. Functions as a skin conditioning agent, typically used in anti-aging formulations. Peptides in this class are generally well-tolerated and non-irritating. No CAS number, GHS codes, or hazard statements. Limited independent safety studies but similar palmitoyl peptides (e.g., palmitoyl pentapeptide-4/Matrixyl) have extensive safety records.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning and anti-aging properties
  • May support collagen synthesis
  • Enhanced bioavailability from lipopeptide structure

Known concerns

  • Limited independent safety data — relatively new ingredient
  • Rare sensitivity reactions possible as with any peptide

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related conditioning agents

82
ACETYL HEXAPEPTIDE-68 AMIDE ACETATE
Conditioning Agent
 82
ACETYL SH-OLIGOPEPTIDE-30 SP
Conditioning Agent
 82
ACTINIDIA POLYGAMA LEAF/STEM EXTRACT
Conditioning Agent
 82
ANTENNARIA DIOICA CALLUS EXTRACT
Conditioning Agent
 82
BACILLUS FERMENT FILTRATE EXTRACT
Conditioning Agent
 82
BACILLUS/SEA SALT FERMENT FILTRATE
Conditioning Agent
 82
BUTYL HYDROXYCYCLOHEXANE CARBOXYLATE
Conditioning Agent
 82
BUTYROYL SH-PENTAPEPTIDE-12 SP
Conditioning Agent

Same plant / compound family

82
PALMITOYL OCTAPEPTIDE-26 AMIDE
Skin Conditioning

Check your shelf

Find PALMITOYL OCTAPEPTIDE-26 in your products.

Scan any cosmetic product with LuxSense to see if it contains PALMITOYL OCTAPEPTIDE-26 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.