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Skin Conditioning

PALMITOYL S-[D-MET2]-DELTORPHIN AMIDE

75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic peptide based on deltorphin (a delta-opioid receptor binder), modified for stability. Used at trace cosmetic levels but its underlying pharmacology earns extra caution and a yellow tier.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Lipid anchor enables stable cosmetic incorporation
  • D-amino acid modification improves stability
  • Synthetic — no animal sourcing

Known concerns

  • Deltorphin is a delta-opioid receptor agonist — pharmacological activity raises regulatory caution for cosmetic use
  • Sparse cosmetic-grade safety dossier
  • Use as a cosmetic ingredient is novel and not widely vetted

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.