Skin Conditioning
PALMITOYL S-[D-MET2]-DELTORPHIN AMIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic peptide based on deltorphin (a delta-opioid receptor binder), modified for stability. Used at trace cosmetic levels but its underlying pharmacology earns extra caution and a yellow tier.
Function
Skin benefits
- Lipid anchor enables stable cosmetic incorporation
- D-amino acid modification improves stability
- Synthetic — no animal sourcing
Known concerns
- Deltorphin is a delta-opioid receptor agonist — pharmacological activity raises regulatory caution for cosmetic use
- Sparse cosmetic-grade safety dossier
- Use as a cosmetic ingredient is novel and not widely vetted
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.