Peptide / multi-peptide signal complex
PALMITOYL TETRAPEPTIDE-132 SH-PENTAPEPTIDE-40 AMIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A cosmetic peptide blend that pairs a palmitoylated tetrapeptide with an SH-pentapeptide amide, marketed for skin-firming and rejuvenation effects at very low formulation percentages in serums.
Function
Skin benefits
- Dual-peptide complex combining a palmitoyl tetrapeptide with a pentapeptide amide for layered signaling
- Palmitoyl carrier well-established for cosmetic dermal delivery
- Typically formulated at sub-percent levels, minimizing systemic exposure
- Class shows good tolerance in repeat-insult patch testing
Known concerns
- Proprietary peptide blend with limited independent toxicology
- Tetrapeptide-132 and SH-pentapeptide-40 lack standalone published safety data
- Stability and bioactivity claims rely largely on supplier white papers
- Potential cost-driven formulation at homeopathic doses limiting actual efficacy
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related peptide / multi-peptide signal complexs
Same plant / compound family
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.