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Skin Conditioning

PALMITOYL TETRAPEPTIDE-135 SH-PENTAPEPTIDE-4 SP AMIDE

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A combined palmitoyl tetrapeptide-135 and pentapeptide-4 lipopeptide, used at trace levels for skin conditioning in anti-ageing formulations. Class has a strong tolerability profile at cosmetic concentrations.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Dual-peptide signal-mimetic design
  • Anti-aging skin conditioning at trace levels
  • Pentapeptide-4 has a long cosmetic track record

Known concerns

  • Sparse public dossier on the combined sequence
  • Niche premium-care ingredient
  • Mild sensitization possible at off-label use levels

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.