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Hair Conditioning

PALMITOYL TETRAPEPTIDE-20 AMIDE

84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A palmitic acid–anchored tetrapeptide amide used to condition hair fibers and improve smoothness. Lipidation aids deposition; gentle at the very low use levels typical of peptide ingredients.

Function

HAIR CONDITIONING

Skin benefits

  • Hair-conditioning film
  • Lipidated peptide improves adsorption on fibers
  • Reduces breakage in stress tests

Known concerns

  • Sparse independent clinical data
  • Possible rare sensitization
  • Low-use-level efficacy varies by formula

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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OLIGOPEPTIDE-251
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OLIGOPEPTIDE-288
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OLIGOPEPTIDE-91 SH-POLYPEPTIDE-2
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Same plant / compound family

70
PALMITOYL TETRAPEPTIDE-20
Peptide

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.