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Skin Conditioning

PANTOLACTONE

CAS 599-04-2; 79-50-5 Updated
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The lactone form of pantothenic acid (vitamin B5) — a small, conditioning humectant closely related to panthenol. Hydrates and soothes skin with an excellent tolerance profile and food-grade safety history.

Skin benefits

  • Skin conditioning humectant
  • Precursor/breakdown form of panthenol (vitamin B5)
  • Improves softness and smoothness
  • Well-tolerated on sensitive skin

Known concerns

  • Limited stand-alone clinical data versus panthenol itself

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.