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Exfoliant

PAPAIN

CAS 9001-73-4 Updated
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Papain — a proteolytic enzyme from papaya that nibbles away dead surface cells for smoother, brighter skin. Generally well-tolerated, but it is a true protein allergen, so sensitive users should patch test.

Skin benefits

  • Gentle enzymatic exfoliation of dead surface cells
  • Smooths and brightens skin texture
  • Plant-derived alternative to acid exfoliants
  • Useful in rinse-off cleansers and masks

Known concerns

  • Documented protein allergen with type I hypersensitivity reports
  • Can sting or irritate compromised or eczematous skin
  • Heat- and pH-sensitive — efficacy varies by formulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related exfoliants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.