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Solvent

PEG-400

CAS 25322-68-3
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A liquid polyethylene glycol used as a solvent and humectant. Decades of safety data and very low irritation; main concern is dioxane purity from PEG synthesis.

Function

BINDINGEMULSION STABILISINGSOLVENT

Skin benefits

  • Versatile humectant and solvent
  • Carrier for actives and fragrances
  • Low acute toxicity in oral and dermal studies

Known concerns

  • Trace 1,4-dioxane unless purified
  • Can enhance penetration of other ingredients
  • Avoid on damaged or burned skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.