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Pelletierine and its salts

CAS 2858-66-4 / 4396-01-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pelletierine And Its Salts is a cosmetic ingredient. Exercise caution due to limited available safety data.

Pelletierine is a tropane alkaloid with anthelmintic properties traditionally used against intestinal parasites. Under EU cosmetics regulation (EC 1223/2009), it is listed in Annex III restricting its use to ≤0.1% as a constituent of other substances. The restriction reflects serious concerns about its systemic toxicity including paralysis and visual disturbances at higher doses.

Known concerns

  • Neurotoxicity at elevated concentrations
  • Prohibited above 0.1% in cosmetic products
  • Risk of paralysis and visual disturbances

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.