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Prohibited drug (CNS stimulant)

Pemoline (INN) and its salts

CAS 2152-34-3
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Pemoline is a discontinued central nervous system stimulant drug, not a cosmetic ingredient. It is prohibited in EU cosmetic products and was withdrawn from medical use due to severe liver toxicity.

Skin benefits

  • No legitimate cosmetic benefit
  • Historically a prescription CNS stimulant only

Known concerns

  • Withdrawn pharmaceutical due to severe liver toxicity
  • Prohibited in EU cosmetics under Annex II
  • Central nervous system stimulant, no role on skin
  • Any cosmetic presence indicates illegal adulteration
  • Carries serious systemic toxicity if absorbed

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.