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Pemoline (INN) and its salts

CAS 2152-34-3
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pemoline (inn) And Its Salts is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Pemoline is a phenethylamine-derived CNS stimulant formerly used as a treatment for narcolepsy and attention disorders. It was withdrawn from pharmaceutical markets due to reported hepatotoxicity including liver failure cases. GHS classifications (H302, H312, H332) reflect acute toxicity concerns. Its pharmaceutical history of liver toxicity makes it entirely unsuitable for cosmetic application.

Known concerns

  • GHS acute toxicity warnings (H302, H312, H332)
  • Market withdrawal due to hepatotoxicity
  • No cosmetic authorization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.