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PENTANEDIONE

CAS 123-54-6
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Pentanedione is a cosmetic ingredient. Exercise caution due to limited available safety data.

Pentanedione (acetylacetone, 2,4-pentanedione) is a beta-diketone used as a solvent and chelating agent. It carries an extensive hazard profile: H226 (flammable), H302 (oral toxicity), H311/H331 (dermal/inhalation toxicity), H320 (eye irritation), H335 (respiratory irritation), H341 (genetic defects), H370/H373 (organ damage), and H402/H412 (environmental toxicity). The compound is regulated under EU REACH and requires careful handling in cosmetic manufacturing.

Skin benefits

  • Chelating agent properties
  • Solvent for cosmetic formulations

Known concerns

  • Acute toxicity (oral, dermal, inhalation: H302/H311/H331)
  • Organ toxicity (H370/H373)
  • Germ cell mutagenicity (H341)
  • Flammability (H226)
  • Environmental toxicity (H412)
  • Extensive multi-route toxicity profile

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.