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Skin Conditioning

PENTAPEPTIDE-119

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A numbered synthetic pentapeptide used for cosmetic conditioning claims. Low hazard at ppm use; efficacy and long-term safety largely supplier-reported.

Pentapeptide-119 is a proprietary synthetic five-amino-acid peptide in the numbered-INCI series, used for skin and hair conditioning claims at low ppm levels. Defined synthetic peptides generally have low irritation and sensitization profiles; the peptide is too small to trigger significant immune responses in most cases. No SCCS or CIR monograph exists for this specific peptide, and independent efficacy data is limited. Purity (residual protecting groups, solvents) and stability of the peptide in finished matrices are supplier-dependent. Typical use is in premium skincare and hair-care serums at very low inclusion. Default-down rubric applies to unreviewed numbered peptides.

Function

ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING, SKIN CONDITIONING - HUMECTANT

Skin benefits

  • Defined synthetic pentapeptide for skin/hair conditioning claims
  • Low use concentration (ppm levels)
  • Low irritation potential

Known concerns

  • Proprietary sequence with manufacturer-driven efficacy data
  • No SCCS/CIR monograph
  • Long-term and immunogenicity data limited
  • Purity and stability supplier-dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.