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Skin Conditioning

PENTAPEPTIDE-21

CAS -
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic pentapeptide composed of glutamine, leucine, serine and tyrosine, incorporated into skincare for potential anti-wrinkle and smoothing benefits. Clean low-irritation profile and no significant documented concerns.

Skin benefits

  • Composed of common, well-tolerated amino acids
  • Used for anti-wrinkle and smoothing effects
  • Stable at typical skincare pH
  • Low irritation potential at cosmetic use levels

Known concerns

  • Limited independent efficacy data
  • Activity is supplier and concentration dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.