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Skin Conditioning

PENTAPEPTIDE-28

CAS -
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A five-amino-acid synthetic anti-ageing peptide used for skin-firming and collagen-support claims. Excellent topical tolerance; low-green reflects solid safety class with limited independent efficacy literature.

Skin benefits

  • Anti-ageing signaling support
  • Reported support for collagen synthesis
  • Low irritation profile typical of short synthetic peptides

Known concerns

  • Independent clinical evidence is thin
  • Efficacy depends on formulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.