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Skin Conditioning

PENTAPEPTIDE-4

CAS -
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A short synthetic peptide (5 amino acids) designed to signal skin cells to produce more collagen — used in firming and anti-ageing serums. Peptide actives are generally very low irritation; data is in-vitro heavy.

Skin benefits

  • Anti-ageing signal peptide
  • Stimulates collagen and ECM in fibroblasts
  • Improves firmness and elasticity claim
  • Low-irritation profile typical of cosmetic peptides

Known concerns

  • Limited large-scale clinical data
  • Stability and penetration depend on formulation
  • Proprietary peptide — independent safety data thin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.