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Skin Conditioning

PENTAPEPTIDE-43

Updated
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A short five-amino-acid signal peptide used in firming/anti-aging serums. Tiny use levels and protein-like chemistry mean low irritation risk, but evidence rests on supplier data.

Function

SKIN CONDITIONING

Skin benefits

  • Marketed as a skin-firming signal peptide
  • Used at trace levels in serums
  • Generally inert at use concentrations

Known concerns

  • Limited public peer-reviewed efficacy data
  • Manufacturer-driven claims, not CIR/SCCS reviewed
  • Possible unspecified peptide allergens

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.