Skin Conditioning
PENTAPEPTIDE-43
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A short five-amino-acid signal peptide used in firming/anti-aging serums. Tiny use levels and protein-like chemistry mean low irritation risk, but evidence rests on supplier data.
Function
Skin benefits
- Marketed as a skin-firming signal peptide
- Used at trace levels in serums
- Generally inert at use concentrations
Known concerns
- Limited public peer-reviewed efficacy data
- Manufacturer-driven claims, not CIR/SCCS reviewed
- Possible unspecified peptide allergens
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.