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Skin Conditioning

PENTAPEPTIDE-53

Updated
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic pentapeptide composed of arginine, glutamate, lysine and serine residues, used in anti-ageing skincare to support extracellular matrix proteins. Clean low-irritation profile and no significant documented concerns.

Skin benefits

  • Composed of common, well-tolerated amino acids
  • Used in anti-ageing skincare
  • Supports extracellular matrix proteins
  • Stable at typical formulation pH

Known concerns

  • Limited independent efficacy data
  • Activity is supplier and concentration dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.