Skin Conditioning
PENTAPEPTIDE-61
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Pentapeptide-61 — a synthetic signalling-peptide active. Plausible at low % but mostly supplier-evidenced.
Pentapeptide-61 is a synthetic five-amino-acid peptide used in skincare for cell-signalling and skin-conditioning claims. Listed in EU CosIng; no dedicated SCCS opinion. Use levels are low (ppm range). Public peer-reviewed safety data is sparse; most information comes from supplier dossiers and in-vitro studies. Patch-test record appears unremarkable at typical use levels but cannot substitute for long-term population data. Evidence level low.
Function
Skin benefits
- Synthetic signalling peptide
- Low-use-level exposure
- Well tolerated in short-term testing
Known concerns
- Proprietary evidence base
- No SCCS dossier
- Thin peer-reviewed data
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.