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Skin Conditioning

PENTAPEPTIDE-61

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pentapeptide-61 — a synthetic signalling-peptide active. Plausible at low % but mostly supplier-evidenced.

Pentapeptide-61 is a synthetic five-amino-acid peptide used in skincare for cell-signalling and skin-conditioning claims. Listed in EU CosIng; no dedicated SCCS opinion. Use levels are low (ppm range). Public peer-reviewed safety data is sparse; most information comes from supplier dossiers and in-vitro studies. Patch-test record appears unremarkable at typical use levels but cannot substitute for long-term population data. Evidence level low.

Function

ANTIMICROBIAL, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Skin benefits

  • Synthetic signalling peptide
  • Low-use-level exposure
  • Well tolerated in short-term testing

Known concerns

  • Proprietary evidence base
  • No SCCS dossier
  • Thin peer-reviewed data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.