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Skin Conditioning

PENTAPEPTIDE-62

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Pentapeptide-62 — another synthetic signalling pentapeptide. Plausible, gentle in short-term use, but evidence is supplier-heavy.

Pentapeptide-62 is a synthetic five-amino-acid peptide marketed for anti-ageing and skin-conditioning claims tied to specific signalling pathways. Listed in EU CosIng; no dedicated SCCS opinion. Use levels are in the parts-per-million range. Public toxicological literature is limited, with supplier-supplied in-vitro and small in-vivo dossiers as the main evidence. Patch-test and clinical tolerance appear routine but are not a substitute for population-scale data. Evidence level low.

Function

ANTIMICROBIAL, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Skin benefits

  • Synthetic signalling peptide
  • Low-use-level exposure
  • Short-term tolerance

Known concerns

  • Proprietary evidence base
  • No SCCS dossier
  • Thin peer-reviewed data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.