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Pentapotassium 2,2’,2’’,2’’’,2’’’’-(ethane-1,2-diylnitrilo)pentaacetate

CAS 7216-95-7
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

This pentapotassium salt of diethylenetriaminepentaacetic acid (DTPA) functions as a chelating agent in cosmetic formulations. It carries significant EU CLP hazard classifications: H319 (eye irritation), H332 (acute inhalation toxicity), H360D (developmental reproductive toxicity), and H373 (specific organ toxicity). DTPA itself is widely used as a safe and effective chelator, but the specific hazard profile of this pentapotassium salt is concerning. The EU Cosmetics Regulation requires particular attention to substances classified for reproductive toxicity under CLP.

Skin benefits

  • Chelates metal ions to improve cosmetic formulation stability
  • May enhance preservative efficacy

Known concerns

  • EU CLP: H360D (developmental reproductive toxicity)
  • H319 eye irritation, H332 inhalation toxicity, H373 organ effects
  • Danger signal word
  • Significant concern for use in cosmetic formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.