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Banned Substance

Pentobarbital sodium [USP:JAN]

CAS 57-33-0 Updated
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A controlled barbiturate sedative — used for anesthesia and veterinary euthanasia. EU Annex II flatly prohibits it in cosmetics. Has no defensible cosmetic application; treat as red.

Skin benefits

  • Primarily a processing aid

Known concerns

  • EU Annex II banned in cosmetics
  • CNS / respiratory depression
  • Schedule II controlled substance in many jurisdictions
  • Lethal overdose potential
  • No cosmetic justification

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.