Skip to content

Banned Substance

Pentobarbital sodium [USP:JAN]

CAS 57-33-0
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A controlled barbiturate sedative — used for anesthesia and veterinary euthanasia. EU Annex II flatly prohibits it in cosmetics. Has no defensible cosmetic application; treat as red.

Skin benefits

  • Primarily a processing aid

Known concerns

  • EU Annex II banned in cosmetics
  • CNS / respiratory depression
  • Schedule II controlled substance in many jurisdictions
  • Lethal overdose potential
  • No cosmetic justification

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related banned substances

3
2-Methoxyethanol [1] and its acetate (2-Methoxyethyl acetate) [2]
Banned Substance
 3
Aniline, its salts and its halogenated and sulphonated derivatives
Banned Substance
 3
Apocynum cannabium L. and its preparations
Banned Substance
 3
DIETHYLENE GLYCOL
Banned Substance
 3
Daminozide
Banned Substance
 3
Dinoterb, its salts and esters
Banned Substance
 3
Dioxane
Banned Substance
 3
Diphtheria antitoxin
Banned Substance

Check your shelf

Find Pentobarbital sodium [USP:JAN] in your products.

Scan any cosmetic product with LuxSense to see if it contains Pentobarbital sodium [USP:JAN] and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.