Skin Conditioning
PEPSIN
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A digestive enzyme from pig stomach that breaks down protein. In skincare it is used for gentle enzymatic exfoliation. Generally safe topically but is animal-derived and can sensitize in rare cases.
Skin benefits
- Enzymatic exfoliation of dead keratin
- Smoother surface texture
- Gentler alternative to acid peels in some formats
Known concerns
- Animal-derived (porcine stomach) — not vegan
- Potential protein sensitization
- Activity varies with pH and storage
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.