Skip to content

Skin Conditioning

PEPSIN

CAS 9001-75-6
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A digestive enzyme from pig stomach that breaks down protein. In skincare it is used for gentle enzymatic exfoliation. Generally safe topically but is animal-derived and can sensitize in rare cases.

Skin benefits

  • Enzymatic exfoliation of dead keratin
  • Smoother surface texture
  • Gentler alternative to acid peels in some formats

Known concerns

  • Animal-derived (porcine stomach) — not vegan
  • Potential protein sensitization
  • Activity varies with pH and storage

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

68
(LEPIDIUM MEYENII/SARCODON ASPRATUS) ROOT WATER
Skin Conditioning
 68
(SH-OLIGOPEPTIDE-78 DI-(S-SILKWORM HEXAPEPTIDE-1)) PEPTIDES
Skin Conditioning
 68
(SH-OLIGOPEPTIDE-78 TRI (S-BAY SCALLOP NONAPEPTIDE-1 SERINE)) PEPTIDES
Skin Conditioning
 68
ABIES ALBA EXTRACT
Skin Conditioning
 68
ABIES VEITCHII LEAF EXTRACT
Skin Conditioning
 68
ABIETOYL DIPEPTIDE-22
Skin Conditioning
 68
ACACIA DECURRENS LEAF EXTRACT
Skin Conditioning
 68
ACACIA VICTORIAE FRUIT EXTRACT
Skin Conditioning

Check your shelf

Find PEPSIN in your products.

Scan any cosmetic product with LuxSense to see if it contains PEPSIN and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.