phenadoxone
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A morphinan-series opioid analgesic not authorized for cosmetic use and regulated as a controlled medicinal substance.
Phenadoxone (6-morpholino-4,4-diphenylheptan-3-one) is a synthetic opioid analgesic of the morphinan series. It is classified as a controlled substance and has no authorization for cosmetic use in any major regulatory jurisdiction. Under EU cosmetics law, it would be considered a prohibited substance. There are no safety data supporting its use in topical applications, and its pharmacological profile makes it entirely unsuitable for cosmetics.
Known concerns
- Prohibited for cosmetic use in the EU
- Synthetic opioid — classified as controlled substance
- No cosmetic safety assessment available
- Pharmacological activity incompatible with cosmetic function
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.