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Fragrance

PHENETHYL BUTYRATE

CAS 103-52-6
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A sweet, rose-peach fragrance ester of phenethyl alcohol and butyric acid. Standard perfumery material with a clean safety record at normal use levels.

Phenethyl butyrate (CAS 103-52-6) is the simple ester of 2-phenylethanol and butyric acid, used at low percentages in fragrances and flavors for sweet, floral, peach-rose notes. It is approved as a flavoring substance by JECFA/FEMA and is listed in IFRA/RIFM databases for fragrance use. No significant GHS hazards beyond mild eye/skin irritation at neat concentrations; not a classified sensitizer. Metabolized rapidly by esterases to the parent alcohol and butyrate. Not an EU Annex III declarable allergen.

Function

PERFUMING

Skin benefits

  • Sweet rose-fruit note
  • Stable ester
  • Common perfumery ingredient

Known concerns

  • Fragrance allergen load consideration
  • Mild neat irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.