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Phenmetrazine hydrochloride [USAN]

CAS 1707-14-8
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phenmetrazine Hydrochloride [usan] is a cosmetic ingredient. Raw material has significant toxicity. Exercise caution due to limited available safety data.

Phenmetrazine is a cyclized amphetamine derivative historically used as an anorectic drug, with acute oral toxicity (H301). It is classified as a prescription-only controlled substance with significant abuse potential and stimulant effects on the central nervous system. It is not listed among EU-approved cosmetic ingredients and is prohibited from cosmetic formulations under EU Cosmetics Regulation 1223/2009.

Known concerns

  • Acute oral toxicity (H301)
  • CNS stimulant activity
  • Controlled substance
  • Prohibited in cosmetic products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.