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Hair dye intermediate (prohibited)

Phenol, 2,2'- methylenebis[4- amino-], dihydrochloride

CAS 27311-52-0 / 63969-46-0
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A bis-aminophenol hair dye intermediate banned in EU cosmetics. Aromatic diamines of this type raise genotoxicity and sensitization concerns, with no SCCS approval for cosmetic use.

Skin benefits

  • Investigated historically as a hair dye intermediate
  • Forms colored compounds via oxidative coupling

Known concerns

  • Listed in EU Annex II as prohibited in cosmetics
  • Aromatic amine with genotoxicity concerns
  • Potential skin sensitizer
  • Suspected carcinogenic potential typical of aminophenol derivatives
  • No safe use level established by SCCS

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.