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PHENOXYPROPANEDIOL

CAS 538-43-2
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phenoxyethanol-related compound used as a preservative booster — helps inhibit microbial growth in cosmetic formulations but may cause sensitization in some individuals.

Phenoxypropanediol (2-phenoxypropane-1,3-diol) is structurally related to phenoxyethanol, with an additional hydroxyl group on the diol side chain. It is used as a preservative and preservative booster in water-based cosmetic formulations. It is listed in CosIng with skin-conditioning function. The compound has been associated with contact sensitization and is subject to IFRA guidelines. It is not banned or severely restricted but is flagged as a potential sensitizer, particularly in leave-on products used at higher concentrations.

Skin benefits

  • Preservative — extends product shelf life and prevents microbial contamination
  • Skin-conditioning humectant properties

Known concerns

  • EU IFRA-regulated — potential sensitizer especially in leave-on products
  • Not suitable for use in lip or oral care products per some guidelines

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.