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Polyphenol antioxidant

PHLORETIN

CAS 60-82-2
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A dihydrochalcone polyphenol naturally found in apples and known for its antioxidant and brightening activity. Often paired with vitamin C and ferulic acid, it supports skin against oxidative stress and uneven pigmentation.

Skin benefits

  • Potent polyphenol antioxidant
  • Synergises with vitamin C and ferulic acid
  • Inhibits melanogenesis and may help even tone
  • Anti-inflammatory and photoprotective in studies

Known concerns

  • Low water solubility complicating formulation
  • Can oxidise and discolour without proper packaging
  • Limited long-term clinical safety data at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related polyphenol antioxidants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.