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PHLORETIN

CAS 60-82-2
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

PHLORETIN is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Phloretin is a dihydrochalcone polyphenol with well-documented antioxidant, anti-inflammatory, and tyrosinase-inhibitory activity. It is not restricted under EU cosmetic regulations and is used in skincare for its skin-brightening and anti-glycation properties. It enhances the efficacy of other antioxidants such as vitamins C and E.

Skin benefits

  • Inhibits tyrosinase enzyme to reduce melanin production and brighten skin
  • Strong antioxidant that protects against UV-induced free radical damage
  • Anti-glycation properties help prevent collagen cross-linking and premature aging

Known concerns

  • Generally safe but may enhance penetration of other actives due to its membrane-disrupting properties

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.