Piperazine
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Piperazine is a cosmetic ingredient. Exercise caution due to limited available safety data.
Piperazine is a cyclic diamine used in some hair dye formulations. Under EU Cosmetics Regulation Annex III, piperazine is restricted to a maximum concentration of 0.1% in hair dye substances. It carries H314 (skin corrosion), H317 (skin sensitization), and H334 (respiratory sensitization) hazard statements.
Known concerns
- Skin sensitizer (H317) and respiratory sensitizer (H334)
- EU Annex III restricted for hair dye use at max 0.1%
- Skin corrosion potential (H314)
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.