Skip to content

Pesticide Synergist

PIPERONYL BUTOXIDE

CAS 51-03-6
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Piperonyl butoxide is a pesticide synergist used in lice and scabies treatments. PubChem GHS flags eye, respiratory, and severe aquatic hazards, and the substance has long term environmental and possible cancer concerns.

Skin benefits

  • Used as a synergist in lice and scabies treatments
  • Increases efficacy of pyrethrin pesticides

Known concerns

  • PubChem GHS: H319 eye irritation, H335 respiratory irritation, H400 and H410 very toxic to aquatic life
  • EPA and EFSA evaluations note possible carcinogenicity in animals
  • Strong environmental persistence and bioaccumulation concerns
  • Pesticide synergist with limited justification in cosmetic formulas
  • Allergic contact dermatitis cases reported

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find PIPERONYL BUTOXIDE in your products.

Scan any cosmetic product with LuxSense to see if it contains PIPERONYL BUTOXIDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.