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Skin Conditioning

PODOPHYLLUM PELTATUM RHIZOME/ROOT EXTRACT

CAS 90063-90-4 Updated
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Mayapple rhizome — the natural source of podophyllotoxin, a prescription antimitotic agent used for genital warts under medical supervision. Its toxicity profile makes it inappropriate for general cosmetic use.

Function

SKIN CONDITIONING

Skin benefits

  • Historical traditional remedy claims
  • Antioxidant flavonoid trace content

Known concerns

  • Contains podophyllotoxin — Rx-only antimitotic agent
  • Severe skin irritation, blistering, systemic toxicity
  • Not appropriate for cosmetic use
  • Reproductive toxicity flags

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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DICTAMNUS ALBUS ROOT EXTRACT
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EPHEDRA DISTACHYA EXTRACT
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HORNET VENOM
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 20
LOBELIA INFLATA
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 20
LYCORIS RADIATA EXTRACT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.