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Surfactant

POLOXAMER 338/PPG-51/SMDI COPOLYMER

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A combined poloxamer/polyglycol/diisocyanate copolymer used as a surfactant-stabilizer. Cured form is inert; residual SMDI isocyanate is the main concern.

Skin benefits

  • Combined surfactant and stabilizer
  • Mild profile
  • Multi-functional polymer

Known concerns

  • SMDI is a methylenediisocyanate derivative
  • Residual isocyanate sensitization risk
  • Sparse public safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

Find POLOXAMER 338/PPG-51/SMDI COPOLYMER in your products.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.