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Preservative

POLYAMINOPROPYL BIGUANIDE

CAS 32289-58-0 [1]/27083-27-8 [2]/28757-47-3 [3]/ 133029-32-0 [4] Updated
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A polymeric biocide used as a cosmetic preservative. EU restricts it to 0.1% leave-on due to inhalation carcinogenicity classification (Cat 2) and skin sensitization reports.

Function

PRESERVATIVE

Skin benefits

  • Broad-spectrum antimicrobial preservative
  • Effective at low concentrations

Known concerns

  • EU restricted to 0.1% leave-on/0.3% rinse-off
  • Carc. Cat. 2 inhalation classification
  • Suspected respiratory sensitizer
  • Skin sensitization reports

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.