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Thickener

POLYHYDROXYETHYLMETHACRYLATE

CAS 25249-16-5
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The polymer used in soft contact lenses, adapted for cosmetic hydrogels and film. Biocompatible at polymer level; watch for HEMA monomer residues.

Polyhydroxyethylmethacrylate (pHEMA, CAS 25249-16-5) is the biocompatible hydrogel polymer originally developed as the material for soft contact lenses — it swells in water to a soft, highly hydrated gel. In cosmetics it functions as a thickener, film-former, and hydrogel base for sheet masks and patches. As a cured polymer it has essentially no skin penetration and an excellent biocompatibility record (from decades of ophthalmic use). The main concern is the free HEMA monomer (2-hydroxyethyl methacrylate), which is a recognized contact allergen in the acrylate/methacrylate family, particularly documented in gel nail products and dental composites. Cosmetic-grade polymers must specify residual-monomer limits. Typical use 0.5-10% in hydrogel products.

Function

BINDING

Skin benefits

  • Soft hydrogel polymer (same as soft contact lens material)
  • Biocompatible hydrogel for cosmetic film or masks
  • Water-binding thickener
  • High-MW polymer — low skin penetration

Known concerns

  • Residual HEMA monomer must be controlled — HEMA is a known contact allergen in nail/dental products
  • Microplastic concerns
  • Limited dedicated cosmetic CIR review for this INCI

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.