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POLYSORBATE 81

CAS 9005-65-6
83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A sorbitol-derived, ethoxylated surfactant (sorbitan monooleate with ~5 EO) widely used to emulsify and stabilise cosmetic formulations at low concentrations.

Polysorbate 81 (sorbitan mono-9-octadecenoate, polyoxyethylene derivative) is a well-established nonionic surfactant used extensively in foods, pharmaceuticals and cosmetics. EU Regulation 1223/2009 lists Polysorbate 80 and related polysorbates in the positive inventory without restrictions; they are not subject to EU Annex III restrictions. They are considered safe for use in rinse-off and leave-on products at levels up to several percent.

Skin benefits

  • Effective emulsifier for oil-in-water systems
  • Can act as a solubiliser for fragrance and essential oils

Known concerns

  • May contribute to food-like allergen concerns in highly sensitive individuals if impure
  • Generally regarded as very safe; no EU restrictions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.