PREGNADIENOL
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A steroid precursor related to progesterone with hormonal activity, making it subject to restrictions in cosmetic products.
Pregnadienol is a C-21 steroid and precursor in progesterone biosynthesis. As a substance with demonstrated hormonal activity, it falls under the EU's endocrine-disrupter framework. The EU Cosmetics Regulation does not list pregnadienol as an authorized cosmetic ingredient, and its use would require a full safety assessment. It is subject to restriction or prohibition depending on concentration and intended use.
Known concerns
- Potential hormonal activity — progesterone-related
- Not listed in EU CosIng authorized substance list
- Requires safety evaluation for cosmetic use
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.