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PROPYLENEDIAMINE

CAS 78-90-0
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Propylenediamine is a cosmetic ingredient. Exercise caution due to limited available safety data.

Propylenediamine (1,2-diaminopropane) is a reactive diamine with severe hazard classifications including H226 (flammable), H302 (harmful if swallowed), H312 (harmful in contact with skin), H314 (causes severe skin burns and eye damage), H311 (toxic in contact with skin), H317 (skin sensitization), H318 (serious eye damage), and H334 (respiratory sensitization) under CLP Regulation 1272/2008. While not explicitly listed in EU Cosmetics Regulation 1223/2009 annexes, the severe hazard profile and sensitization classifications severely limit its cosmetic use.

Skin benefits

  • Used as a pH adjuster or intermediate in some cosmetic formulations

Known concerns

  • Skin corrosion H314 and serious eye damage H318
  • Acute toxicity H302, H312, H311
  • Respiratory sensitization H334
  • Skin sensitization H317
  • Flammable H226

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.