PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A diaminopyrimidine derivative with GHS Warning classification for acute oral toxicity (H302) that is used in some hair growth and anti-androgenic cosmetic formulations; the heterocyclic amine structure raises concerns about potential genotoxicity.
Pyrrolidinyl Diaminopyrimidine Oxide is a pyrimidine N-oxide derivative where the pyrrolidinyl ring is attached to the diaminopyrimidine core. The GHS classification H302 indicates acute oral toxicity concern, though inhalation and dermal routes may differ. Pyrimidine derivatives can interfere with nucleotide metabolism, and the oxide functionality adds additional reactivity.
Skin benefits
- Some derivatives are used for hair growth promotion and anti-androgenic effects in scalp treatments
Known concerns
- GHS H302 acute oral toxicity classification
- Diaminopyrimidine heterocycle may interfere with skin nucleotide metabolism
- Limited long-term skin safety data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.