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Banned / Annex II

QUASSIN

CAS 76-78-8 / 75991-65-0
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Quassin — a bitter quassinoid from Quassia wood, banned in EU cosmetics under Annex II. Cytotoxic and reproductive-toxicity signals make it unsuitable for skincare.

Skin benefits

  • No safe cosmetic use; intensely bitter quassinoid

Known concerns

  • EU Cosmetics Regulation Annex II — banned
  • Quassinoid with cytotoxic and pharmacological activity
  • Reported reproductive toxicity in animal studies
  • Not appropriate for skin contact products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.