QUATERNIUM-15

42

Caution

CAS Number: 4080-31-3 / 51229-78-8

About QUATERNIUM-15

A formaldehyde-releasing quaternary ammonium preservative with known skin sensitization risk, restricted under EU Annex II/1386 and subject to specific labeling requirements.

Detailed Analysis

Quaternium-15 is a widely documented formaldehyde releaser used as a preservative in cosmetic formulations. It is listed in EU Annex II/1386 as a restricted preservative specifically due to its formaldehyde-releasing mechanism and the associated risk of allergic contact dermatitis. Its use is permitted but strictly controlled, and it must be declared on the ingredient list. Formaldehyde-releasing preservatives have been declining in use due to consumer sensitivity and regulatory pressure in the EU.

Skin Benefits

  • Effective broad-spectrum preservative in water-based cosmetics

Known Concerns

  • Formaldehyde releaser — risk of allergic contact dermatitis
  • Skin sensitizer (known allergen)
  • Restricted under EU Annex II/1386
  • Subject to specific labeling requirements in EU

Safety Score

42

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.