quinestradol
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An estrogenic steroid derivative with potent hormonal effects, subject to restriction or prohibition in most cosmetic regulatory frameworks.
Quinestradol (estradiol 3-cyclopentyl ether; 3-cyclopentyl 17-beta-estradiol ether) is an estradiol ether with estrogenic activity. As a potent estrogenic substance, it is subject to EU restriction under Annex III or considered a substance requiring particular evaluation before cosmetic use. Its pharmacological potency precludes general cosmetic use, and it is primarily relevant as a prescription or herbal medicinal ingredient.
Known concerns
- Potent estrogenic activity — endocrine disruption risk
- EU restriction required for any cosmetic use
- Pharmaceutical potency inappropriate for cosmetic formulations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.