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Conditioning Agent

R-(METHIONYL HEXAPEPTIDE-40 SH-POLYPEPTIDE-119 OLIGOPEPTIDE-164)

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A biotech peptide active with more uncertainty than a simple moisturizer, though limited skin penetration keeps risk below the worst cases.

R-(METHIONYL HEXAPEPTIDE-40 SH-POLYPEPTIDE-119 OLIGOPEPTIDE-164) is a recombinant protein or fusion peptide produced by fermentation for skin-conditioning or protective claims. Large proteins usually penetrate intact skin poorly, but this is still a biologically complex, less-established ingredient class than ordinary emollients or humectants. The main concern is limited independent long-term cosmetic safety data.

Function

SKIN CONDITIONING

Skin benefits

  • Softens skin

Known concerns

  • Novel biotech peptide with limited independent safety data
  • Protein-based ingredients can trigger sensitivity in some users

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.